Radiology

The Demirci Bio-Acoustic MEMS in Medicine Lab (BAMM) specializes in creating technologies to manipulate cells in nanoliter volumes to enable solutions for real world problems in medicine including applications in infectious disease diagnostics and monitoring for global health, cancer early detection, cell encapsulation in nanoliter droplets for cryobiology, and bottom-up tissue engineering.
areas of research are :

Micro nano scale technologies in medicine

Extracellular vesciles

Early Cancer Detection

Biomedical engineering

microrobotics

The PIMed Laboratory has a multi-disciplinary direction and focuses on developing analytic methods for biomedical data integration, with a particular interest in radiology-pathology fusion to facilitate radiology image labeling . The radiology-pathology fusion allows the creation of detailed spatial labels, that later on can be used as input for advanced machine learning, such as deep learning.

CAR (chimeric antigen receptor) T-cell therapy has shown promising results in patients with leukemia and lymphoma. However, therapy response in patients with solid tumors is highly variable. An imaging test, which could directly visualize CAR T-cells in patients would greatly improve our understanding of factors that lead to successful treatment outcomes. Immune cells can be labeled with clinically translatable iron oxide nanoparticles, which can be detected with magnetic resonance imaging (MRI).

My lab focuses on translating advanced MRI into clinical practice. In Alzheimer’s disease, we are investigating the nature of iron deposition to understand how iron interacts with inflammation, amyloid, and tau in the progression of AD. We bring to this disease the full arsenal of imaging: ultra-high resolution MRI of human AD specimens coupled with novel histological methods including x-ray microscopy and electron microscopy. We bring this armamentarium full circle to living human imaging with 7.0T MR and multi-tracer PET-MR.

The Laboratory for Integrative Personalized Medicine (PIMed) is directed by Dr. Mirabela Rusu, PhD,  and is part of the School of Medicine, Department of Radiology, Division of Integrative Biomedical Imaging Informatics at Stanford University.   

The Pitteri laboratory uses mass spectrometry to identify, quantify, and characterize proteins in complex biological and clinical samples.  We are focused on using proteins and their post-translational modifications to better understand biology and to answer clinical problems in health and disease states.  Currently, a main focus of the lab is developing and implementing new methods to study protein glycosylation in cancer.

Department URL:
https://canarycenter.stanford.edu/

Micro nano scale technologies in medicine

Extracellular vesciles

Early Cancer Detection

Biomedical engineering

microrobotics

Dr. Mirabela Rusu directs the Laboratory for Integrative Personalized Medicine (PIMed), which is part of the School of Medicine, Department of Radiology, Division of Integrative Biomedical Imaging Informatics.

Microfludics

Diagnostics

Early Cancer Detection

Exosomes

Our lab's research lies at the interface of biology, engineering, nanotechnology, and medicine. We develop and apply translational micro/nanotechnologies to study cellular heterogeneity and complex biological systems for single cell analysis and precision medicine.  At this unique nexus, we apply key biological principles to design engineering platforms. Our research philosophy is to apply these platforms to fundamentally understand and address the mechanisms of disease (i.e., cancer, infections).