Appointing a postdoctoral scholar with expertise in causal inference, machine learning, and analyses of electronic health record (EHR) data. The postdoc will work with Assistant Professor Zachary Butzin-Dozier (Department of Pediatrics, Division of Clinical Informatics, and Department of Medicine, Division of Computational Biology) on research using large-scale EHR data sources, including Epic Cosmos and PEDSnet.
The Stanford Solutions Science Lab is seeking a highly-motivated postdoctoral scholar to lead a large-scale, community-based, clinical trial of behavioral treatment for childhood obesity. The Solutions Science Lab designs transdisciplinary, community-based programs to improve the health of children and their families and evaluates them in real world clinical trials.
We study immunology of infectious diseases and host-microbe interactions. Our research program employs murine infection models and brings together immunology, tissue biology, microbiology, and genetics to uncover fundamental mechanisms of tissue immunity and immunophysiology during persistent bacterial infection.
My research group is currently focused on understanding brain function and inter-brain synchrony during naturalistic social interaction. We use ultra-portable near-infrared spectroscopy (NIRS) to address specific scientific questions with an emphasis on multi-modal assessment (e.g., behavioral, physiological, environmental setting, and eye-tracking in addition to functional NIRS). This overall scientific apprach is called "interaction neuroscience:.
My laboratory's overall goal is to (i) understand the mechanisms of right heart failure in children and adults with congenital heart disease and (ii) to develop biomarkers as a plasma signature of myocardial events to better understand the mechanisms of heart failure, improve monitoring of disease progression, early detection of heart failure and risk-stratification.
The Davis laboratory is looking for post-doctoral scholars interested in the study of cancer. We use single-cell, high-dimensional approaches in primary patient materials to identify cells associated with poor clinical outcomes. We have a focus on childhood leukemia, neuroblastoma and Ewing sarcoma. Once identified, we can further interrogate mechanisms of resistance in candidate cell populations and develop new approaches for treatment.
Our lab has several major focuses:
1. Using iPSC-derived cardiomyocytes to develop a better understanding of hypertrophic cardiomyopathy and congenital heart disease.
2. The role of alterations in mitochondrial structure and function in normal physiology (such as exercise) and in disease such as dilated and hypertrophic cardiomyopathy.
3. Single cell analysis of mitochondrial function reveals significant heterogeneity.
Our team is committed to finding ways to improve maternal and infant health outcomes and equity by leading research that identifies effective leverage points for change, from upstream 'macro' social and structural factors, to downstream 'micro' clinical factors through a collaborative research approach that integrates epidemiologic approaches with community engagement and systems thinking.
Disparities are prominent in maternal and infant health, so a lot of our work is centered on equity. Focusing on highest-risk groups will improve health for everyone.
Current Research and Scholarly Interests
My laboratory's overall goal is to (i) understand the mechanisms of right heart failure in children and adults with congenital heart disease and (ii) to develop biomarkers as a plasma signature of myocardial events to better understand the mechanisms of heart failure, improve monitoring of disease progression, early detection of heart failure and risk-stratification.
Our research program integrates concepts of chemical biology, protein engineering and structure biology to design new therapeutic leads and generate probes to study biological processes. A key focus of our lab is insulin, an essential hormone in our body to reduce blood glucose levels. We generate synthetic libraries of insulin analogs to select for chemical probes, and investigate natural insulin molecules (e.g. from the venom of fish-hunting cone snails!) to develop novel therapeutic candidates.