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Open Postdoctoral position, faculty mentor Tanja Gruber

Important Info

Faculty Sponsor (Last, First Name): 
Gruber, Tanja
Stanford Departments and Centers: 
Ped: Hematology-Oncology
Ped: Stem Cell Trans
Postdoc Appointment Term: 
TBD
Appointment Start Date: 
TBD
Group or Departmental Website: 
https://pedhemonc.stanford.edu/
https://med.stanford.edu/ptrm.html
How to Submit Application Materials: 

Interested applicants should submit by email the required application materials to Tanja A. Gruber, M.D., Ph.D., Chief, Division of Hematology Oncology Stem Cell Transplant and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine.  Email:  tagruber@stanford.edu.

Postdoctoral fellowship opportunity
 
Pathogenesis of Fusion Oncogene Driven AML
Laboratory of Tanja Andrea Gruber, M.D., Ph.D. (Pediatrics, Stanford Cancer Institute)
Division of Hematology Oncology Stem Cell Transplant and Regenerative Medicine
Department of Pediatrics
 
An opportunity is available for a highly motivated postdoctoral fellow who is interested in the pathogenesis of fusion oncogene driven AML towards a career in academics, biotechnology or pharmaceutical industry. The applicant should have a strong background in cancer biology, molecular biology, biochemistry, and preferably with experience working with mammalian cells and mouse models of cancer, especially leukemia. There will be opportunities to work with physicians, translational researchers, and scientists.
 
Leukemia cell lines, primary mouse and human hematopoietic cells, and mouse models will be used. Technologies in the lab include standard biochemistry techniques (Western blot analysis, real-time PCR, immunoprecipitations), FACs/sorting, colony assays, lentiviral and retroviral transductions, transplantation experiments, xenograft models and bioluminescence, barcoding and single cell tracking of hematopoietic cells, RNA-seq , CUT&RUN sequencing, and shRNA/CRISPR library screening. Knowledge in bioinformatics would be helpful for sequencing analyses.
 
The intent of these studies is to understand transcriptional regulation by the CBFA2T3-GLIS2 oncogene and the effects on hematopoiesis using two established murine models developed in our lab. Our long-term goals are to utilize this information to identify therapeutic targets for translational studies.

Required Qualifications: 
  • This position is for postdoctoral fellows who have received a Ph.D. in molecular biology, cellular biology, or biochemistry and have completed their Ph.D. and graduate level training within the past 5 years.
  • Experience in hematopoiesis, flow cytometry and cell and animal models of leukemia or cancer are preferred.
  • The candidate is expected to be able to work independently and as part of a team.
  • We are looking for individuals with excellent communication, teamwork, data processing, problem solving, written, and oral presentation skills.
  • U.S. Citizenship, Green Card or Permanent Residency is not required.
Required Application Materials: 
  • A curriculum vita
  • Letter of interest
  • Contact information for 3 references

 

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.