Open Postdoctoral position, faculty mentor Tanja Gruber

Important Info

Faculty Sponsor First name: 
Tanja
Faculty Sponsor Last Name: 
Gruber
Stanford Departments and Centers: 
Pediatrics, Hematology Oncology Stem Cell Tranplantation and Regenerative Medicine
Postdoc Appointment Term: 
1-year term (Renewal is based on performance -- Max of a 5 years)
Appointment Start Date: 
As Soon As Possible
How to Submit Application Materials: 

Interested applicants should submit the required application materials by email to Aronne Schwartz, administrative assistant to Tanja A. Gruber, M.D., Ph.D., Chief, Division of Hematology Oncology Stem Cell Transplant and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine.  Email: aronne@stanford.edu 

Does this position pay above the required minimum?: 
No. The expected base pay for this position is the Stanford University required minimum for all postdoctoral scholars appointed through the Office of Postdoctoral Affairs. The FY25 minimum is $76,383.

Immunotherapies Targeting Pediatric AML

Laboratory of Tanja Andrea Gruber, M.D., Ph.D. (Pediatrics, Stanford Cancer Institute) 
Division of Hematology Oncology Stem Cell Transplant and Regenerative Medicine
Department of Pediatrics

An opportunity is available for a highly motivated postdoctoral fellow who is interested in immunotherapeutic approaches for fusion oncogene driven AML towards a career in academics, biotechnology or pharmaceutical industry. The applicant should have a strong background in immunology, cancer biology, molecular biology, and preferably with experience working with mammalian cells and mouse models of cancer, especially leukemia. There will be opportunities to work with physicians, translational researchers, and scientists.  

Primary human hematopoietic and leukemia cells, and an established humanized mouse model will be used.   Technologies in the lab include standard biochemistry techniques (Western blot analysis, real-time PCR, immunoprecipitations, cloning), FACs/sorting, colony assays, lentiviral and retroviral transductions, transplantation experiments, xenograft models, peptide stimulation assays, single cell sequencing, and RNA-seq. Knowledge in bioinformatics for the analysis of sequencing data is preferred. 

The intent of these studies is to determine the immunogenicity of tumor associated antigens identified in our humanized mouse model as well as the characterization of expanded TCR clones and their potential therapeutic applicability. Additional avenues of study will be to identify potential CART targets for pediatric AML using sequencing datasets followed by functional validation in murine models.  Our long-term goals are to utilize this information to develop cellular therapies for pediatric AML. 

Required Qualifications: 
  • This position is for postdoctoral fellows who have received a Ph.D. in immunology, molecular biology, or cellular biology and have completed their Ph.D. and graduate level training within the past 5 years.  
  • Experience in immunotherapy and cell and animal models of leukemia or cancer are preferred.  
  • The candidate is expected to be able to work independently and as part of a team.
  • We are looking for individuals with excellent communication, teamwork, data processing, problem solving, written, and oral presentation skills.
Required Application Materials: 
  • Curriculum vita
  • Letter of interest
  • Contact information for 3 references

 

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.