Posted on Mon, 02/24/2025 - 12:56

Important Info

Faculty Sponsor (Last, First Name): 
Plevritis, Sylvia
Stanford Departments and Centers: 
Biomedical Data Sciences
Postdoc Appointment Term: 
Minimum two years
Appointment Start Date: 
As soon as possible
Group or Departmental Website: 
https://plevritislab.stanford.edu/
How to Submit Application Materials: 

Please complete a questionnaire and upload your documents here.  Only applications received through Qualtrics will be reviewed. Applications will be accepted until the position is filled.

Does this position pay above the required minimum?: 
Yes. The expected base pay range for this position is listed in Pay Range field. The pay offered to the selected candidate will be determined based on factors including (but not limited to) the qualifications of the selected candidate, budget availability, and internal equity.
Pay Range: 
$74,128 - $75,611

Postdoctoral Scholarship - Cancer Biologist in Tumor Spatial Biology

A cancer molecular biologist at the level of Postdoctoral Fellow is sought to work in a hybrid (wet/dry) systems biology laboratory of Professor Sylvia Plevritis at Stanford University to study tumor spatial biology via single cell spatial analysis of the tumor microenvironment. Projects aim to reveal molecular mechanisms of drug resistance based on intercellular and intracellular regulation, with a focus on combination therapies that account for cell-cell interactions. Experimental model systems will include cancer cell lines, organoid/assembloid models, and clinical tumor samples. Projects will primarily rely on perturbation assay via targeted treatments and manipulation of gene expression in cell culture, and patient-derived models.

Required Qualifications: 
  • The ideal candidate should have a PhD in the field of molecular and cellular cancer biology, relevant publications, curiosity for science and innovative thinking, and high fluency in English.
  • Experience with mammalian cell culture models, 3D co-culture of cancer cells with other compartments of the tumor microenvironment, organoids and/or patient-derived organoids models.
  • Fluorescence microscopy and immunohistochemistry, multiplex immunofluorescence imaging is highly desirable.
  • Experience in genomics is required and spatial -omics, including spatial transcriptomics is highly desirable
  • Use of lentiviral delivery systems for gene silencing or gene editing by CRISPR-Cas9 is required.
  • Experience with flow cytometry and/or mass cytometry analysis is desirable.
  • Interest in learning new technologies is mandatory. Basic R programming skills or the interest in learning programming is highly desirable.
  • A successful candidate will interact closely with computational biologists and be responsible for designing and executing experiments that will, in part, validate computationally-derived regulatory interactions of the tumor microenvironment.
Required Application Materials: 
  • Cover letter describing relevant research experiences, accomplishments, interests, and goals
  • Curriculum vitae
  • Name and contact information of three references

 

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.