Important Info
If you are passionate about reproductive biology and want to work in a highly collaborative and innovative environment, we encourage you to apply. To apply, please email the required application materials to both Dr. Matteo Molè (mmole@stanford.edu) and Dr. Xiaojie Qiu (xiaojie@stanford.edu).
Project Description
Join a pioneering project at Stanford University to create “A Spatial Transcriptomic Atlas of Embryo-Endometrial Crosstalk During Implantation and Human Embryo Development”. This position is funded by a new collaborative grant between the laboratories of Dr. Xiaojie Qiu (Genetics & Computer Science) and Dr. Matteo Molè (Obstetrics & Gynecology).
Our goal is to explore the “black box” of early human pregnancy by mapping the precise gene activity and cell-cell interaction between the developing embryo and maternal endometrium. This work addresses a critical factor in human reproduction, as implantation failure remains a major reason for IVF treatment failure and early pregnancy loss.
You will work at the interface of the Molè and Qiu labs as the lead experimental scientist or computational/AI scientist on this project. This is a unique opportunity to work in a cutting-edge, interdisciplinary environment, leveraging a novel in-vitro model of the human uterus and/or cutting edges machine learning techniques to make foundational discoveries in reproductive medicine. The annual salary for this full-time position starts at $76,383, dependent upon skills and previous experience. Initial appointment is 1 year with expected renewal after the first year for additional years.
Position Summary:
We are seeking 1-2 highly motivated Postdoctoral Scholars to lead a multifaceted project focusing on investigating fundamental mechanisms of human embryo development. This is a unique opportunity to work at the intersection of developmental biology, spatial genomics, computational biology and AI. We aim to appoint one postdoctoral scholar with strong computational skills and a second experimental postdoctoral scholar to work at the interface between the two labs to integrate experimental and computational data.
Key Responsibilities:
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Building 3D complex endometrial models and optimizing in vitro implantation assays.
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Culturing human embryos and generating stem cell-based embryo models.
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Tissue sectioning for advanced spatial transcriptomic analysis.
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Leading the analysis of single-cell and spatial transcriptomics data.
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Applying and developing the analysis framework for spatiotemporal modeling.
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Publication in top-tier journals, and apply and obtain competitive funding if interested.
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Maintain meticulous research records and support operational/reporting responsibilities associated with clinical research.
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A PhD in computational biology, bioinformatics, genetics, AI, machine learning, computer science, or a related field. Demonstrated experience analyzing single-cell and/or spatial genomics datasets is a plus but not necessary. Proficiency in programming (e.g., Python, R) and familiarity with common bioinformatics tools and packages.
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A PhD in developmental biology, cell biology, regenerative medicine, or a related field. A required background in cell biology and embryology, with extensive experience in mammalian cell culture, ideally with human pluripotent stem cells (hPSCs). Demonstrated experience in performing single-cell and/or spatial genomics experiments is a plus but not necessary.
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Experience in carrying out independent and collaborative research.
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Proven experience with protocol development, software development, computational modeling and research leadership. Excellent organizational skills and the ability to maintain meticulous records.
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Ability to plan and prioritize own work to meet deadlines, including using initiative to plan research programs.
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Working collaboratively with others and building working relationships with stakeholders at all levels.
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Demonstrate inclusivity and respect for all.
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Commitment to personal development and updating of knowledge and skills.
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CV
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Cover letter outlining your research interests, career goals, and specific qualifications for the role
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Contact information for 3 professional references