An institutionally funded post-doctoral position is immediately available in the laboratory of Dr. Frederick Dirbas in the Department of Surgery, Division of Surgical Oncology. His laboratory focuses on basic and translational research in the molecular, cellular, and functional changes following FLASH Radiation Therapy in preclinical models of breast cancer. The lab’s goal is to move FLASH RT towards clinical use in humans by comparing and contrasting the effects FLASH vs conventional radiotherapy on normal tissue in immunocompetent animal models as well as syngeneic and xenograft models of breast cancer. Dr. Dirbas works closely with Dr. Billy Loo in Stanford’s Department of Radiation Oncology, with additional close collaborations with Dr Michael Clarke and Dr. Aaron Newman in Stanford’s Institute for Stem Cell Biology and Regenerative medicine.
The postdoctoral fellow will work in a collaborative team to perform FLASH irradiation experiments in mice and study changes in tissues by immunohistochemical and immunofluorescence imaging of tissue sections, among multiple other analytical tools.
Applicants with research experience in mouse research (tumor models and normal tissue physiology), small animal irradiation and/or imaging, cancer cell biology including cancer stem cells, radiobiology, and familiarity with bulk and single cell RNA sequencing, are particularly encouraged to apply.
• PhD, MD/PhD degree in Cancer Biology, Molecular and Cellular Biology, Genetics, Cancer Stem Cells, Immunology, or relevant discipline
• Experience in mouse handling, tumor models (immunocompetent and/or immunodeficient), molecular biology, microscopy, immunohistochemical and immunofluorescence imaging preparation and analysis of tissue sections and assays
• Experience in manuscript writing/publication and research presentations at conferences
* - Experience in flow cytometry, RNA extraction, spatial transcriptomics is preferred but not required
1. Cover letter
2. Current CV with publication list
3. Contact information for three references