Posted on Sun, 11/03/2024 - 10:43

Important Info

Faculty Sponsor (Last, First Name): 
Kim, Brian
Other Mentor(s) if Applicable: 
Thomas Quertermous, Paul Cheng
Stanford Departments and Centers: 
Med: Cardiovascular Medicine
Postdoc Appointment Term: 
2-4 years
Appointment Start Date: 
ASAP
Group or Departmental Website: 
http://kimlab.stanford.edu
How to Submit Application Materials: 

To apply, submit the required application materials, or find out more information, please contact Dr. Brian Kim (kimjb at stanford edu). The position will remain open until filled.

Does this position pay above the required minimum?: 
No. The expected base pay for this position is the Stanford University required minimum for all postdoctoral scholars appointed through the Office of Postdoctoral Affairs. The FY25 minimum is $73,800.

Join us in unraveling the genomic mysteries of environmental cardiovascular diseases and making a lasting impact on public health!

 The CLEAN Lab (kimlab.stanford.edu) focuses on investigating the mechanisms underlying environmental toxicant-induced cardiovascular diseases and gene-environment interactions, with a specific emphasis on identifying modifiers of response to known toxicants leading to vascular diseases such as coronary artery disease. We are seeking a highly motivated postdoctoral research candidate with a background in molecular biology, genetics, and/or toxicology, with strong preference for proficiency in bioinformatics and programming to analyze and present results from large genomic datasets including bulk-RNA and DNA sequencing, single-cell sequencing (RNA, ATAC), and whole genome sequencing datasets. The prospective candidate will investigate the genomic basis of atherosclerotic vascular disease, with emphasis on identifying mechanism and modifiers of response to known toxicants leading to vascular disease, including tobacco, vaping, and air pollution. 

Major focus will be on a funded project to identify the drivers of gene-environment/toxicant interaction including the integration of large-scale human genome-wide association (GWAS) with bulk and single-cell (e.g. scRNA-seq and scATAC-seq) sequencing, optimization of in-vitro and in-vivo exposure protocols, and use of cutting-edge informatics to prioritize causal variants for validation using functional genomics, including CRISPR. The overall goals of this work are to define novel disease targets and context-specific mechanisms underlying vascular diseases, ultimately to inform new treatment and prevention strategies. Other opportunities include use of animal model of disease to dissect the mechanism of environmentally responsive genes on atherosclerosis.

To apply or find out more information, please contact Dr. Brian Kim (kimjb at stanford edu) and applicants should attach the following: current CV (include brief statement of research interests), and contact information for three references. The position will remain open until filled.

Required Qualifications: 

1. Ph.D. in a relevant field (e.g., genetics, bioinformatics, molecular biology, toxicology, pharmacology). 

2. Proficiency in bioinformatics, programming, and tools for the analysis of large genomic datasets and single-cell dataset, including R, linux, python, Seurat/Signac. 

3. Background in toxicology, with experience in environmental toxicants affecting cardiovascular health.

4. Demonstrated ability to work independently and collaboratively within a research team.
 

5. Excellent communication skills and a track record of scholarly publications.

Required Application Materials: 
  •  Current CV (include brief statement of research interests)
  • Contact information for three references

 

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.