Important Info
Please submit application materials here: https://app.smartsheet.com/b/form/741083b2e2e549c3af714cb095b07d92
A postdoctoral fellow position is available in the laboratory of Dr. Bereketeab Haileselassie in the Department of Pediatrics Division of Critical Care Medicine at Stanford University. Our research focuses on understanding how alterations in mitochondrial dynamics impact cellular metabolism and function during various inflammatory disorders. Our resent work has demonstrated that impairments in mitochondrial dynamics including excessive fission and stalled mitophagy mediate the accumulation and extracellular release of mitochondrial byproducts which promote a pro-inflammatory response. This molecular process plays a significant role in various acute and chronic inflammatory disorders including acute Graft versus Host Disease (GVHD), a common and severe complication following hematopoietic stem cell transplantation.
Our group works on developing targeted tools which abrogate impairments in mitochondrial dynamics as therapeutic candidates for the treatment of this devastating complication of HSCT.
This position will provide the candidate with an opportunity to lead interdisciplinary research projects with a strong focus on understanding how pre-transplant conditioning regiments impact mitochondrial dynamics and function. Furthermore, this position will provide an opportunity to characterize the impact of cell free mitochondrial byproducts on immune phenotypes as it relates to GVHD.
We are looking for a highly motivated individual who has a strong background in stem cell transplantation and immunology. Candidates who are interested in broadening their knowledge and skillset in mitochondrial biology would best fit this position.
- PhD in cell biology, molecular biology, stem cell biology, developmental biology, immunology, or cancer biology.
- The candidate should have expertise in cell and molecular biology, and animal handling in addition to some of the following preferred laboratory techniques: cell culture, gene editing/transcription and virus transfection, flow cytometry.
- The candidate is expected to have the ability to work independently and as part of a team.
- Self-initiative and motivation, excellent communication, teamwork, data processing, written and oral presentation and problem-solving skills are desired.
- English proficiency is required.
- CV with references