Skip to content Skip to navigation

Open Postdoctoral position, faculty mentor Alice Bertaina

Important Info

Faculty Sponsor (Last, First Name): 
Bertaina, Alice
Postdoc Appointment Term: 
TBD
Appointment Start Date: 
TBD
How to Submit Application Materials: 

To apply, email the required application materials to Alice Bertaina MD, PhD at aliceb1@stanford.edu c/o Zhenyu Yao MD, PhD at zhenyuy@stanford.edu.

A postdoctoral fellow position is available in the laboratory of Dr. Alice Bertaina in the Department of Pediatrics, Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine at Stanford University. Our innovative research program uses cutting-edge technologies to optimize a novel strategy of graft manipulation (alpha/beta T-cell/CD19 B-cell depleted haploidentical stem cell transplantation) for treating children with malignant and non-malignant disorders. Our group aims to understand the impact of the graft composition on the outcome of children affected by malignant and life-threatening non-malignant disorders, further engineer the graft to improve graft-versus-leukemia and minimize graft-versus-host disease and enable the use of gamma/delta (γδ) T cells for cancer immunotherapy.

This position will provide the candidate with an opportunity to lead interdisciplinary research projects with a strong focus on understanding how to predict/prevent leukemia relapse after stem cell transplantation. We are looking for a highly motivated individual who has a strong background in stem cell transplantation and immunology. The successful candidate will conduct a translational project focused on empowering adoptive cancer immunotherapy by precise engineering of human hematopoietic stem/progenitor cells and T lymphocytes. Specifically, the successful candidate will lead a project aimed at using genome editing to optimize the manufacturing of donor-derived CAR T cells by creating variations of the construct with different promotor strengths and signaling domains, to identify the ideal combination to achieve the best antileukemia activity against low disease burden and, subsequently, evaluate their activity in mouse models.

Required Qualifications: 
  • PhD in cell biology, molecular biology, stem cell biology, developmental biology, immunology, or cancer biology.
  • The candidate should have expertise in cell and molecular biology, and animal handling in addition to some of the following preferred laboratory techniques:
    • cell culture, gene editing/transcription and virus transfection, flow cytometry.
  • The candidate is expected to have the ability to work independently and as part of a team.
  • Self-initiative and motivation
  • Excellent communication
  • Teamwork
  • Data processing
  • Written and oral presentation
  • Problem-solving skills are desired
  • English proficiency is required
Required Application Materials: 
  • CV/resume
  • Cover letter outlining research interests and experience
  • Contact information for 3 references

 

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.