To apply please email the required application materials to Beatrice Ochoa at firstname.lastname@example.org.
The Bertaina Laboratory has an open position for a highly creative and motivated postdoctoral fellow with a strong interest in stem cell transplantation and immunology. The candidate should be a highly qualified scientist with excellent written and verbal communication skills.
The successful candidates will conduct a translational project focused on empowering adoptive immunotherapy by precise engineering of human hematopoietic stem/progenitor cells and lymphocytes. In particular, this postdoctoral fellow will work in optimizing hematopoietic stem cell transplantation for rare and complex genetic disorders, including Schimke Immune-Osseous Dysplasia (SIOD). The project will benefit from a highly integrated, multidisciplinary and supportive research environment, such as that of the Pediatric Stem Cell and Regenerative Medicine Division.
Our focused research program uses cutting-edge technologies to optimize an innovative strategy of graft manipulation (ab T-cell depleted haploidentical stem cell transplantation) for curing children with non-malignant disorders. In particular, our group aims to understand the impact of the graft composition on the outcome of children affected by rare and complex immune-genetic disorders. The biggest focus of our research is on gd T cells, a subset of CD3+ cells combining conventional adaptive features with rapid, innate-like responses that place them in the initiation phase of immune reactions. In addition, they recognize tumor cells without recourse to the classical major histocompatibility complex (MHC) presentation. For this reason, they are the ideal cellular target for strategies of post- HSCT adoptive immunotherapy.
This position will provide the candidate with an opportunity to lead interdisciplinary research projects within these areas with a strong focus on understanding how to optimize the outcome of stem cell transplantation in children with rare and complex immune-genetic disorders.
- The successful candidates must have a PhD or MD/PhD in which s/he has gained knowledge in cell and molecular biology, stem cell biology, developmental biology, immunology, or cancer biology.
- Specific skills and personal attributes required include: excellent writing and presentation skills, high energy multi-tasker, supremely organized with exquisite attention to detail, ability to work independently in a dynamic, fast paced team environment, computer and technology savvy, strong expertise with molecular and cellular biology.
- Collaborative team spirit, strong communication skills, positive attitude and adherence to highest ethical principles are necessary to be considered.
- Updated CV
- Complete contact information for three references
- Short cover letter describing their past research experience, career goals and a statement of future research interest (1 page)