Tim Assimes

Our investigative focus is the design, conduct, analysis, and interpretation of human molecular epidemiology studies of complex cardiovascular disease (CVD) related traits including coronary atherosclerosis and risk factors for coronary atherosclerosis. In addition to performing discovery and validation population genomic studies, we use contemporary genetic studies to gain important insight on the causal and mechanistic nature of associations between purported risk factors and adverse cardiovascular related health outcomes through instrumental variable analyses and genetic risk score association studies of intermediate phenotypes.  Successful applicants will be immersed in cutting-edge molecular epidemiology studies of traits related to cardiovascular disease using large scale population biobanks including the Million Veteran Program, the Women‚Äôs Health Initiative, and the UK Biobank, with the goal of improving biological understanding, refining risk prediction, and discovering new therapeutic targets.