Samuel Yang

Associate Professor
Stanford Departments and Centers: 
Surgery, Emergency Medicine
Research Interests: 

The investigative interests of my lab falls within the general themes of

1) Developing precision diagnostics for infectious diseases that integrates pathogen, host, and drug response information. This includes

  • Developing high-content, near-patient, diagnostic system for rapid broad pathogen detection and characterization.
  • Integrating multi-omics molecular and phenotypic data layers with novel computational approaches into advanced diagnostics and predictive analytics for acute infections.
  • Developing personalized, rapid antimicrobial susceptibility analysis system based on early response kinetics in physiological conditions to inform antimicrobial choice, dosage, and duration.
  • Exploring the clinical utility of serum bactericidal assay as a humoral immune functional assessment in the prediction of bloodstream infections. 

2) Understanding the functional roles of extracellular DNA in neutrophil extracellular traps and biofilm

  • As a DNAzyme that drives bactericidal effects and immunopathologies.