Professor
Stanford Departments and Centers:
Medicine, Hematology
Institute for Stem Cell Biology and Regenerative Medicine
Stanford Cancer Center
T32 affiliation:
Cancer Etiology, Prevention, Detection and Diagnosis
Program in Translational and Experimental Hematology
Training in Pediatric Nonmalignant Hematology and Stem Cell Biology
Training Program in Hematopoietic Cell Transplantation
Research Interests:
The Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). In parallel, the lab also investigates normal human hematopoiesis and hematopoietic stem cells. Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for both normal and malignant human hematopoietic cells. A major focus of the lab is the investigation of pre-leukemic hematopoietic stem cells in human AML.