Our lab is dedicated to discovering the underpinnings of immune-related diseases in the heart. Many cancer drugs may cause immune-related toxicity in the heart, including severe myocarditis, making it difficult for patients with cancer to get the life-saving treatments they need. We have previously discovered that several key types of immune cells may be involved in potentiating disease. We are currently performing experiments to pin down the underlying mechanisms of how immune cells may cause various inflammatory heart diseases. We use a combination of precision medicine-oriented techniques including single-cell RNA-seq, TCR-seq, and CyTOF as well as classical molecular biology, cell modeling and animal modeling to answer mechanistic questions about the pathogenesis of cardiac inflammatory diseases, with the goals of discovering therapeutic targets which can be brought to the patient bedside.