Assistant Professor
Stanford Departments and Centers:
Pediatrics
Genetics
Research Interests:
The Gifford lab is focused on defining the complex genetic and molecular mechanisms that are necessary for faithful cardiovascular development and how perturbation of these mechanisms can lead to disease. We use both stem cell and rodent experimental models to:
- characterize the cellular interactions involved in cardiovascular development
- define the oligogenic mechanisms underlying congenital heart diseases, such as hypoplastic left heart syndrome and left ventricular noncompaction
- explore the link between congenital heart disease and neurodevelopmental delay
We also collaborate closely with clinicians, for example on a project integrating cardiac imaging and genetic data to predict adverse cardiac outcomes. Ultimately, we hope to make personalized medicine a reality for those that suffer from CHD and associated comorbidities, such as autism.