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Potential Mentors for PRISM Candidates

The following faculty have expressed interest in the PRISM program and most are actively recruiting. Consider how their research interests align with yours as you choose potential mentors. Other faculty members may also be recruiting. 

For School of Medicine faculty, browse SoM Departments or find details about individual faculty members in the School of Medicine via Community Academic Profiles (CAP). For faculty outside of the School of Medicine, browse departments in the Natural SciencesEarth Sciences, or Engineering and find details about individual faculty members in these areas via Stanford Profiles.

Please check back often -- more lab profiles will be added throughout the application period. 

 

Faculty

Research Interests

School of Earth, Energy, & Environmental Sciences

Geophysics

William Ellsworth
Professor (Research)

Ellsworth Lab

My research interests can be broadly defined as the study of active faults, the earthquakes they generate and the physics of the earthquake source. A major objective of my work is to improve our knowledge of earthquake hazards through the application of physics-based understanding of the underlying processes. I have also long been committed to earthquake risk reduction, specifically through the transfer of scientific understanding of the hazard to people, businesses, policymakers and government agencies.  I co-direct the Stanford Center for Induced and Triggered Seismicity where we pursue a broad range of fundamental and applied research into the underlying causes of human-induced earthquakes and solutions to mitigate their risk.

Earth System Science

Eric Lambin
Professor

Lambin Lab

My research team conducts land system change studies in different parts of the world. Using methods that link remote sensing data with socio-economic data, our research reveals cross-scale dynamics causing tropical deforestation, forest transitions, and dryland degradation. Our research is strongly focused on solutions for sustainable land use. Our current research is on the link between economic globalization and land use. National land use policies alone are not sufficient to achieve global forest conservation, given a leakage (or geographic displacement) of land use change to other places and other spillover effects. We analyze how the governance of global supply chains in agricultural and forestry products could lead to more sustainable land use. We are particularly interested in sustainable sourcing commitments by the private sector. Using rigorous methods, we evaluate the impact of these supply chain interventions on land use. One of the key finding is that the effectiveness of a private governance of land use depends on supportive public policies. We therefore analyze systematically the interactions between governments, NGOs, and companies for the design and implementation of interventions for sustainable land use. I am completely open to other research ideas in that general space.

Graduate School of Education

Graduate School of Education

Ari Kelman
Associate Professor

EDJS

Religion and Education in all its forms:  school, out-of-school, self-directed, technologically mediated, and across the lifespan. 

School of Engineering

Chemical Engineering

Elizabeth Sattely
Assistant Professor

Sattely Lab

My laboratory is focused broadly on plant chemistry and is deeply invested in pathway discovery. Despite the important roles of plant natural products in plant and human health, very few complete plant biosynthetic pathways are known. This lack of knowledge limits our understanding of natural product mode of action in plants and prevents access to engineered pathways. New plant genome sequences and synthetic biology tools have enabled three research areas in my lab: 1) methods for accelerating pathway discovery in plants (especially for clinically used therapeutics), and 2) discovering new molecules from plants that are important for plant fitness, and 3) using metabolic engineering in plants as a tool to systematically and quantitatively determine the impact of plant molecules on human and plant health and ultimately optimize plant fitness and crop nutrient load. I am looking for postdocs who are interested in joining an interdisciplinary team of scientists and engineers to discover how plant natural products are made and their mode of action, and develop new tools for engineering biosynthetic pathways. Our vision is to use engineered biosynthesis to reveal mechanisms by which natural products from plants contribute to plant fitness and human health.

Electrical Engineering

John Pauly
Professor

Pauly Lab

My group does medical imaging research.  Particular areas of interest are image guided interventions, image reconstruction, and fast imaging methods. We are particularly interested in the application of machine learning methods for accelerating image acquisition and reconstruction.

Materials Science & Engineering

Eric Appel
Assistant Professor

Appel Lab

The underlying theme of my research program integrates concepts and approaches from supramolecular chemistry and natural/synthetic materials to tackle healthcare challenges of critical importance to society. My research aims to apply rationally designed molecular recognition motifs in materials science and biology to meet the need for novel minimally invasive strategies for the precisely tuned and sustained delivery of complex combinations of molecular reagents to control the behavior of the immune system. Both vaccines and immunotherapies seek to coordinate a complex, multifaceted immune response to protect the body from pathogens or fight off cancer. We seek to develop materials to enable a critical avenue for elucidating what molecular levers must be pulled, how hard, and for how long, to produce robust, targeted, and long-lived immune responses.

Mechanical Engineering

Sindy Tang
Associate Professor

Tang Lab

We are seeking a joint NIST-Stanford postdoctoral fellow to help develop millimeter-scale cryofluidic systems for working with and handling functional biomaterials (i.e., cells, cultures, environmental samples). Ideal candidate should be able to work independently, and also with a diverse team of scientists, engineers, and designers to rapidly prototype and iterate on the design and testing of integrated systems (i.e., build a 'box', test a 'box', debug and repeat). Expertise and prior experience in working with fluids in low temperature systems (e.g.,-80C) and interfacing low temperature fluidic systems to other mechanical and electronic systems strongly desired. US citizenship required. 

School of Humanities & Social Sciences

Biology

Dominique Bergmann
Professor

Bergmann Lab

The overall goal of my research program is to understand how stem cell-like populations are created and maintained in the context of an intact and environmental responsive tissue.  We use the Arabidopsis stomatal lineage for these studies as this epidermal cell lineage distills many of the features common to all tissue development: stomatal precursor cells are chosen from an initially equivalent field, they undergo asymmetric and self-renewing divisions, they communicate among themselves to establish pattern and they terminally differentiate into stable, physiologically important cell-types.  In the past decade, we have developed the stomatal lineage into a conceptual and technical framework for the study of cell fate, stem-cell self-renewal and cell polarity. Currently, we are especially interested in: (1) using new single-cell technologies to capture transcriptomic and chromatin state information about cells as they transit through various identities (stem cell-like, committed, differentiated, and reprogrammed); (2) using new ‘in vivo biochemical’ approaches to identify plant-specific cell polarity complexes and how these guide changes in cell shape, size and fate; (3) computational modeling of pattern formation in the epidermis, and (4) testing how environmental information impacts developmental choices and robustness.   

Biology

Xiaoke Chen
Assistant Professor

Chen Lab

Our lab study neural circuits underlying motivated behaviors. We currently focused on a thalamic nucleus: the paraventricular nucleus of the thalamus (PVT). The PVT is reciprocally connected with regions involved in top-down control, such as the prefrontal and insular cortices. It also receives extensive inputs from the hypothalamus and brainstem which convey motivational arousal and homeostatic states. The PVT is the only thalamic nucleus that innervate all structures in the extended amygdale system. Combining the Pavlovian conditioning paradigm and in vivo recording, we found PVT response to both appetitive and aversive stimuli and their predicting cues. Its response amplitudes are proportional to stimulus intensity and modulated by changes in homeostatic state or behavioral context. Optogenetic inhibition of the PVT activity suppresses associative learning (Zhu et al., 2018, Science, in press). In the context of drug-associated learning and memory, we found PVT-to-NAc pathway as a prominent neuronal substrate mediating the physical signs and negative emotion accompany with opiate withdrawal. We further established a causal link between morphine-induced plasticity in the PVT-to-NAc circuits and the expression of withdrawal symptoms (Zhu et al., 2016, Nature).

Biology

Jan Skotheim
Associate Professor 

Skotheim Lab

My overarching goal is to understand how cell growth triggers cell division. Linking growth to division is important because it allows cells to maintain a specific size range to best perform their physiological functions. For example, red blood cells must be small enough to flow through small capillaries, whereas macrophages must be large enough to engulf pathogens. In addition to being important for normal cell and tissue physiology, the link between growth and division is misregulated in cancer.
 
Today, thanks to decades of research into the question of how cells control division, we have an extensive, likely nearly complete parts-list of key regulatory proteins. Deletion, inhibition, or over-expression of these proteins often results in changes to cell size. However, the underlying molecular mechanisms for how growth triggers division are not understood.  How do the regulatory proteins work together to produce a biochemical activity reflecting cell size or growth? Since we now have most of the parts, the next step to solving this fundamental question is to better understand how they work together.

Chemistry

Bianxiao Cui
Associate Professor

Cui Lab

My research objective is to develop new biophysical methods to advance current understandings of cellular machinery in the complicated environment of living cells. We bring together state-of-the-art nanotechnology, physical science, engineering and molecular and cell biology, to advance current understandings of biological processes.  Currently, there are two major research directions: (1) Developing nanoscale tools to probe electric activities and cellular processes at the cell-material interface. In this area, we have developed nanoscale electric probes, structural probes and optical probes with high sensitivity and subcellular localization. We identify membrane curvature as one of the crucial biochemical signals that translate nanoscale surface topography into intracellular signaling. (2) Employing optical, magnetic, and optogenetic tools to understand nerve growth factor (NGF) signaling in neurons.  By adapting a variety of microscopy, optogenetic, nanotechnology and biochemical tools, we aim for a deeper understanding of NGF signaling in normal neurons and neurodegenerative diseases.

Chemistry

Tom Markland
Associate Professor

Markland Lab

Our research focuses on the theory and simulation of chemical systems to address problems at the interface of quantum mechanics and statistical mechanics, with applications ranging from chemistry and biology to geology and materials science. Our research frequently explores theories of hydrogen bonding, the interplay between structure and dynamics, systems with multiple time and length-scales, and quantum mechanical effects. Particular current interests include proton and electron transfer in materials and enzymatic systems, atmospheric isotope separation, and the control of catalytic chemical reactivity in heterogeneous environments.

Physics

Bruce Macintosh
Professor 

Macintosh Lab

Our group works with  adaptive optics - optical systems that correct for aberrations using mirrors that change their shape thousands of times per second. This can allow telescopes located on the Earth to correct for atmospheric turbulence and produce diffraction-limited images, which we use to study giant extrasolar planets through direct imaging with the Gemini Planet Imager (GPI) instrument. Direct imaging of extrasolar planets separates the light of the (faint) planet and (bright) star, allowing us to measure the spectrum of young self-luminous giant exoplanets. We are currently planning an upgrade to GPI, adding a faster adaptive optics system using predictive control, and more accurate wavefront sensors. 
 
We are studying this technology for more powerful instruments on the ground and space. We are also exploring applications in biology - microscopes that can look into tissues. 

Psychology

Michael Frank
Associate Professor

Frank Lab

How do we learn to communicate using language? I study children's language learning and how it interacts with their developing understanding of the social world. I am interested in bringing larger datasets to bear on these questions and use a wide variety of methods including eye-tracking, tablet experiments, and computational models. Recent work in my lab has focused on data-oriented approaches to development, including the creation of large datasets like Wordbank and MetaLab. I also have a strong interest in replication, reproducibility, and open science; some of our research addresses these topics. 

Psychology

Russell Poldrack
Professor

Poldrack Lab

My lab uses the tools of cognitive neuroscience to understand the organization of brain systems involved in decision making and executive function.  We also develop neuroinformatics tools to help improve the ability of researchers to share their data, perform reproducible research, and aggregate across datasets.  We are interested in a postdoc who would expand the diversity of our group and has a commitment to open and transparent science, strong computational abilities, and interest in the processing of neuroimaging data, particularly fMRI data but also extending to other forms such as diffusion and structural MRI. 

School of Medicine

Anesthesiology, Perioperative and Pain Medicine

Nima Aghaeepour
Assistant Professor (Research)

Aghaeepour Lab

We are a machine learning lab with a primary focus on predictive modeling of clinical outcomes using multiomics biological assays. Our research covers a wide range of unconventional yet high-impact topics ranging from space medicine to the integration of mental health, physical health, immune fitness, and nutrition in various clinical settings. We are primarily a computational immunology research group but depending on the problem at hand, our datasets include clinical measurements, readouts from advanced wearable technologies, and various genomics and proteomics assays.
 
Our group has a strong commitment to translating research findings into actionable products. We encourage (and financially support) our postdoctoral fellows to receive extensive training in entrepreneurship and business management from Stanford’s School of Business. This provides an excellent opportunity for a candidate who is not only interested in participating in state-of-the-art academic research, but is also interested in exploring industrial and entrepreneurial career trajectories.

Anesthesiology, Perioperative and Pain Medicine

Eric Gross
Assistant Professor, UTL line

Gross Lab

Aldehydes are produced during surgery stemming from cellular injury. There are also environmental sources of aldehyde exposure such as cigarettes and alcohol.

One aspect of the lab is studying how we can better protect tissue from aldehyde toxicity during ischemia-reperfusion injury by using  both in vivo and cellular models of ischemia-reperfusion injury.  We are also developing sensitive methods to monitor aldehyde production and metabolism which we anticipate translating to clinical use for surgeries through real time monitoring.

Our laboratory also has an interest in studying the cardiopulmonary effects of e-cigarettes and are applying our extensive experience in cardiovascular research to address how aldehydes present in e-cigarettes impact the cardiovascular system.

Anesthesiology, Preoperative and Pain Medicine

Vivianne Tawfik
Assistant Professor

Tawfik Lab

Chronic pain affects 1 in 3 Americans at a huge cost to society. A more thorough understanding of the basic mechanisms contributing to chronic pain is crucial to the development of therapies that target the likely unique underlying causes of diverse pain conditions. Projects in the Tawfik Lab use clinically-informed basic science approaches to further understand the crosstalk between the nervous system and the immune system in several mouse models of perioperative injury. In particular, we have an interest in CNS glial cells (astrocytes and microglia) which, after injury, can contribute to central sensitization and persistence of pain. Preclinical use of glial modulators has been successful at reversing existing pain, however, translational efforts have thus far failed. We strive to further understand glial subtypes and functional phenotypes in order to better tailor glial-directed therapies. Our projects involve collaborations with several other labs in Neurology, Radiology and Anesthesiology in a collegial environment focused on rigorous science and close mentorship.

Biochemistry

Aaron Straight
Associate Professor 

Straight Lab

Our laboratory studies the dynamics and organization of eukaryotic genomes. Every eukaryotic cell must compact its DNA into the nucleus while maintaining the accessibility of the DNA to the replication, repair, expression and segregation machinery. Eukaryotes accomplish this feat by assembling their genomes into chromatin and folding that chromatin into functional compartments. We are studying four key processes in the eukaryotic nucleus: 1) the genetic and epigenetic basis for centromere formation that enables chromosome segregation, 2) the role of noncoding RNAs in structuring the genome and regulating gene expression, 3) the formation of silent heterochromatin and its role in genome organization and 4) the activation of the embryonic genome at the maternal to zygotic transition. We rely on biochemistry, quantitative microscopy and genomics to probe genome dynamics in vitro and in living systems. Our goal is to uncover the core principles that organize eukaryotic genomes and to understand how genome organization controls organismal function.

Biochemistry and Pathology

Ellen Yeh
Assistant Professor

Yeh Lab

Malaria caused by Plasmodium spp parasites has an enormous disease burden that disproportionately affects the world’s poorest and youngest.  Our research focuses on elucidating the biology and function of the parasite’s unique plastid organelle, the apicoplast, which is a key anti-malarial drug target.  We take innovative approaches to meet the challenges of studying this complex organism, including a chemical rescue that generates ‘mutant’ parasites lacking their apicoplasts! Investigation of Plasmodium biology offers both the potential for important global health impact and an opportunity to explore fascinating eukaryotic biology.

Bioengineering

Michael Fischbach
Associate Professor

Fischbach Group

Small molecules from the human microbiota. Many of the most widely used human medicines come from soil and marine bacteria, including treatments for cancer, infectious disease, diabetes, and organ transplant. We have recently found that bacteria from a surprisingly underexplored niche -- the human body -- are prolific producers of drug-like small molecules. We are identifying small molecules from gut- and skin-associated bacteria, studying their biosynthetic genes, and characterizing the roles they play in human biology and disease. 
 
Using synthetic ecology to control microbiome metabolism. One of the most concrete contributions the microbiome makes to human biology is to synthesize dozens of metabolites, many of which accumulate in human tissues at concentrations similar to what is achieved by a drug. We are engineering gut and skin bacterial species to produce new molecules, and constructing synthetic communities whose molecular output is completely specified.

Bioengineering

Bo Wang
Assistant Professor

Wang Lab

Flatworms include more than 44,000 parasites, many of which are pathogenic to humans or livestock, with flukes, tapeworms, and hookworms as notorious representative species. They typically transmit through multiple hosts using several drastically different body plans specialized for infecting and reproducing within each host. Although flatworms’ complex life cycles were established over a century ago, little is known about the cells and genes they use to optimize their transmission potential, thereby limiting our ability to develop effective therapeutic and preventive strategies. We aim to develop a comprehensive cellular and molecular understanding of the stereotypical life cycle of a blood fluke, Schistosoma mansoni, and identify novel targets to block it. Schistosomes cause one of the most prevalent but neglected infectious diseases, schistosomiasis. With over 250 million people infected and a further 800 million at risk of infection, schistosomiasis imposes a global socioeconomic burden comparable to that of tuberculosis, HIV/AIDS, and malaria. This project will use novel single-cell technologies to build a schistosome "cell atlas", and map the developmental states of their stem cells as they produce all other cell types in the schistosome body plans.

Chemical and Systems Biology

James Chen
Professor and Chair

Chen Lab

Our laboratory integrates synthetic chemistry, genetics, and developmental biology to investigate the molecular mechanisms that control tissue formation, regeneration, and oncogenic transformation. Our research group is currently focused on three major areas: (1) small-molecule and genetic regulators of the Hedgehog signaling pathway; (2) optochemical and optogenetic tools for studying tissue patterning with spatiotemporal precision; and (3) zebrafish models of vertebrate development.

Dermatology

Kevin Wang
Assistant Professor 

Wang Lab

The Wang Lab takes an interdisciplinary approach to studying fundamental mechanisms controlling gene expression in mammalian cells. Our work shows how epigenetic mechanisms such as DNA methylation, chromatin modifications, and RNA influence chromatin dynamics to affect gene regulation. OUR LAB IS CURRENTLY FOCUSED ON: How various dynamic epigenetic changes in chromatin structure impact gene expression during stem cell pluripotency/self-renewal, cellular differentiation, and reprogramming; How three-dimensional chromosomal structure and dysregulation contribute to development of diseases such as aging and cancer; and How to create novel genome engineering tools to interrogate the noncoding genome and the epigenome.
 
The long-term goal of The Wang Lab is to translate our understanding of these complex mechanisms to studies of human diseases.

Medicine - Biomedical Informatics

Olivier Gevaert
Assistant Professor 

Gevaert Lab

The Gevaert lab focuses on multi-scale data fusion in oncology: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. Previously I pioneered data fusion work using Bayesian and kernel methods studying breast and ovarian cancer. My subsequent work concerned the development of methods for multi-omics data fusion. This resulted in the development of MethylMix, to identify differentially methylated genes, and AMARETTO, a computational method to integrate DNA methylation, copy number and gene expression data to identify cancer modules. Additionally, my lab focuses on linking molecular data with cellular and tissue-level phenotypes. This led to key contributions in the field of imaging genomics/radiogenomics involving work in lung cancer and brain tumors. Our work in imaging genomics is focused on developing a framework for non-invasive personalized medicine. In summary, my lab has an interdisciplinary focus on developing novel algorithms for multi-scale biomedical data fusion.

Medicine – Cardiovascular Medicine

Tim Assimes
Associate Professor

Assimes Lab

Our investigative focus is the design, conduct, analysis, and interpretation of human molecular epidemiology studies of complex cardiovascular disease (CVD) related traits including coronary atherosclerosis and risk factors for coronary atherosclerosis. In addition to performing discovery and validation population genomic studies, we use contemporary genetic studies to gain important insight on the causal and mechanistic nature of associations between purported risk factors and adverse cardiovascular related health outcomes through instrumental variable analyses and genetic risk score association studies of intermediate phenotypes.  Successful applicants will be immersed in cutting-edge molecular epidemiology studies of traits related to cardiovascular disease using large scale population biobanks including the Million Veteran Program, the Women‚Äôs Health Initiative, and the UK Biobank, with the goal of improving biological understanding, refining risk prediction, and discovering new therapeutic targets. 

Medicine - Endocrinology, Gerontology, & Metabolism

Justin Annes
Assistant Professor 

Annes Lab

My lab works towards developing novel therapeutics for Diabetes and Endocrine Cell Tumors. To achieve this goal, we develop (1) new animal disease models  to better understand disease pathogenesis (biologists), (2) innovative screening/discovery  platforms to identify potential therapeutic targets and lead compounds (biologists/biochemists) and  (3) synthesize new chemical entities with desired activities for therapeutic application (medicinal chemists). Hence, typical projects in the lab are interdisciplinary and collaborative where the work of biologists is supported by the power of synthetic chemistry . A major current theme in the lab is addressing the challenge   of cell-targeted drug delivery, i.e. how can we develop a medicine that only acts on the cell type of interest and apply this to (a) a regenerative therapy for diabetes and (b) the treatment of cancer.   If you're excited about disease modeling and/or drug discovery (in diabetes and cancer) my lab might be a good match for you.  

Medicine - Pulmonary and Critical Care

Vinicio de Jesus Perez
Assistant Professor
UTL Medicine

deJesus Perez Lab

Several studies have now shown the importance of Wnt signaling for heart tissue repair in the left ventricle, but fewer studies have been done to understand Wnt’s role in right ventricle hypertrophy. The remodeling of the right ventricle during pulmonary hypertension leads to changes and impairment in the vasculature, cardiomyocyte dysfunction and fibrosis.  Our lab has shown the importance of Wnt signaling in pulmonary angiogenesis and we hypothesize that Wnt expression in the cardiac cells is critical to improve their response to the pressure load and with this, prevent heart failure. Using cardiac muscle cells and endothelial cells derived from healthy and idiopathic PH patients; we are screening and comparing the expression of several Wnts between the two groups in order to find Wnt candidates for our study. We aim to find a Wnt-associated gain of function in heart cells after injury during PH

Medicine – Nephrology

Vivek Bhalla
Assistant Professor

Bhalla Lab

Dr. Bhalla's two primary research interests are in the interaction of the kidney in diabetes and hypertension.

We use molecular, biochemical, and transgenic approaches to study mechanisms of physiologic and aberrant solute handling and its consequences for health and disease. Our current experiments have implications for diabetes, hypertension, and kidney disease in obesity and insulin resistance. Specifically, we are studying the mechanisms of insulin-sensitive glucose uptake in the kidney in the setting of peripheral insulin resistance. We have previously examined aberrant sodium handling and are now focused on mechanisms of diminished potassium secretion in the setting of insulin resistance.

We also study mechanisms of susceptibility to diabetic kidney disease including the role of the endothelium to regulate inflammation and kidney injury. Specifically, we are studying the role of a glomerular endothelial-enriched gene, Esm-1, and its effects on inflammation and albuminuria using deletion and over-expression approaches in vivo.

Microbiology & Immunology

Holden Maecker
Professor (Research) 

Maecker Lab

A major theme in our group is to define metrics of immune competence in various settings, including cancer immunotherapy, organ transplantation, allergy, and chronic viral infection.  We use CyTOF mass cytometry, often in combination with other technologies, to broadly survey immune features at the cellular level, then examine links between features or groups of features and clinical outcome.  A long-term goal is to create an assay of global immune competence that could predict risk for various immune-related outcomes in both healthy individuals and in disease.

Microbiology and Immunology

Jan Carette
Associate Professor

Carette Lab

Our lab is interested in the host pathways that determine the susceptibility of humans to viral disease. Viruses constantly evolve to exploit host machineries for their benefit whilst disarming host restriction mechanisms. Discovery of host proteins critical for viral infection illuminates basic aspects of cellular biology, reveals intricate virus host relationships, and leads to potential targets for antiviral therapeutics.

Microbiology & Immunology

Peter Sarnow
Professor 

Sarnow Lab

We are studying the interactions of flaviviruses (hepatitis C virus, Dengue virus, Zika virus) with host factors in both mosquito and human hosts. Specifically, we are using genetic and biochemical approaches to examine RNA-RNA and RNA-protein interactions that modulate viral pathogenesis. These are are being performed in organoid cell cultures which display many characteristics of humans tissues. Single cell sequencing approaches reveal  interaction in infected and uninfected bystander cells. The ultimate goal is to uncover novel targets for antiviral interventions.

Molecular & Cellular Physiology

Merritt Maduke
Associate Professor

Maduke Lab

The Maduke laboratory at Stanford University is seeking a postdoctoral scholar to study the molecular mechanisms of chloride-selective channels and transporters. Chloride channels and transporters are expressed ubiquitously, with defects giving rise to human diseases of kidney and bone, disorders of blood-pressure regulation, and epilepsy.  Projects in the lab seek to understand the molecular basis for these functions using a combination of electrophysiology, biochemistry, and a variety of structural and spectroscopic techniques, tightly integrated with results from computational collaborations. Experience in electrophysiology, structural biology, or membrane protein biochemistry is helpful but is not necessary.  More important is a strong personal motivation and willingness to learn.

Relevant publications include:

Khantwal, C.M., et al. (2016) Revealing an outward-facing open conformational state in a CLC Cl-/H+ exchange transporter. Elife Jan 22;5. pii: e11189. doi: 10.7554/eLife.11189.

Abraham, S.J., Cheng, R.C., Chew, T.A., Khantwal, C.M., Liu, C.W., Gong, S. Nakamoto, R.K., and Maduke, M. (2015). 13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1. J Biomol NMR, 61(3-4), 209-26.

Han, W., Cheng, R.C., Maduke, M.* and Tajkhorshid, E.* (2014). Water Access Points and Hydration Pathways in ClC H+/Cl− Transporters. PNAS, 111: 1819–1824. PMCID: PMC3918786

Molecular and Cellular Physiology

Miriam Goodman
Professor 

wormsense Lab

The wormsenseLab seeks to decipher the genetic, molecular and physical basis of touch sensation and its disruption by mechanical and chemical stress, such as exposure to elevated glucose in diabetes and chemotherapeutic drugs. We use a combination of genetics, electrophysiology, and quantitative analysis of behavior and also develop new tools for delivering and measuring mechanical force.  The lab is recruiting postdocs interested in interdisciplinary training with the Dionne group to develop nanoparticle sensors of mechanical force.

Neurobiology

Andrew Huberman
Associate Professor

Huberman Lab

Our specific main goals are to:

1. Discover strategies for halting and reversing vision loss in blinding diseases.

2. Understand how visual perceptions and arousal states are integrated to impact behavioral responses.

We use a large range of state-of-the-art tools: virtual reality, gene therapy, anatomy, electrophysiology and imaging and behavioral analyses.

Neurobiology

Jennifer Raymond
Professor 

Raymond Lab

The goal of our research is to understand the algorithms the brain uses to learn. A fundamental feature of our neural circuits is their plasticity, or ability to change. How does the brain use this plasticity to tune its own performance? What are the learning rules that determine whether a neural circuit changes in response to a given experience, and which specific neurons or synapses are altered?  Our research integrates molecular, cellular, systems and computational neuroscience approaches in mice to uncover the logic of how the cerebellum implements learning. 

Neurology

John Huguenard
Professor

Huguenard Lab

I direct the NIH supported T32 Epilepsy postdoctoral training program, with faculty broadly interested in the cellular/circuit basis of normal brain excitability and how it is disrupted in the disease of epilepsy.  My particular interest is in large scale brain rhythms occuring during childhood absence epilepsy as studied in animal models.

Neurology

Elizabeth Mormino
Assistant Professor 
 

Mormino Lab

Alzheimer's disease pathology begins decades before clinical symptoms of dementia are present, providing an important opportunity to understand early disease and the impact of this disease on cognitive aging.  We combine multimodal neuroimaging and genetics to determine how AD changes and risk factors influence subtle cognitive decline in older individuals. We have a particular focus on PET imaging of Amyloid and Tau proteins, but also work with structural and functional MRI data. The ultimate goals of our work are to improve our ability to predict who is most at risk for dementia, and to understand the time course of brain changes that occur decades before clinical symptoms are present.  We are specifically recruiting trainees with expertise in genetics, neuroimaging, or neuropsychology, to work on large scale multimodal imaging-genetic studies.

Neurosurgery

Melanie Hayden Gephart
Associate Professor

Hayden Gephart Lab

We seek greater understanding of the genetic and epigenetic mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We currently study the capacity of cellular and cell-free nucleic acids to inform treatment choices in patients with brain tumors, mechanisms of brain tumor cell migration, and identify potentially targetable genes and pathways. Our laboratory space lies at the heart of the Stanford campus between the core campus and the medical facilities, emblematic of the translational aspects of our work.

Neurosurgery

Suzanne Tharin
Assistant Professor

Tharin Lab

We study the roles of microRNAs in cortical projection neuron development, with an emphasis on corticospinal motor neurons. We have identified a group of mircoRNAs specifically enriched in corticospinal motor neurons during their development and are investigating their functions in cortical progenitors in vitro and in vivo, as well as in ES cells.

Oncology

James Ford
Professor

Ford Lab

The focus of our research is understanding the role of genetic changes in cancer genes in the risk and development of common cancers and on manipulating DNA repair mechanisms for the prevention and treatment of cancer. Solid tumors often exhibit high levels of reactive oxygen species (ROS) resulting in oxidative damage and the generation of 8-oxoguanine (8-oxoG), a common source of mutations and DNA damage in the cell. ROS can be generated by multiple mechanisms including activating RAS mutations, exposure to chemical carcinogens and ionizing reagents, or as a by-product of metabolic processes in the cell.  ROS likely impacts the initiation of BRCA-mutated triple negative breast cancer (TNBC) through the accumulation of mutations in the cell.  Up-regulating base excision repair (BER) pathways is a potentially viable approach to inhibiting tumorigenesis in BRCA-mutated individuals by reducing mutagenesis. We have identified small-molecule activators of BER and are exploring their mechanism of action and activity in cells and tumorogenesis models in mice. We are seeking a Postdoctoral scholar to work in this area who is

well-versed in tissue culture, cellular assays, and molecular biology techniques. Experience and a willingness to work with mice is preferred.

Ophthalmology

Alfredo Dubra
Associate Professor

Dubra Lab

Our lab is part of the Byers Eye Institute at Stanford University. We seek to reveal ocular, vascular, neuro-degenerative and systemic diseases through the development, translation and application of novel optical ophthalmic imaging technologies. Our current projects are focused on developing novel instrumentation and imaging techniques for non-invasive visualization of retinal structure and function at the microscopic scale. We pursue this through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines. A major focus of our work is technology translation and dissemination, which is furthered through collaboration with scientists and clinicians working on the most advanced therapies for vision preservation and restoration.

Ophthalmology

Jeffrey Goldberg
Professor 

Goldberg Lab

We work on the cellular and molecular basis of neuronal survival and axon growth relevant to neuroprotection and regeneration, and on differentiation and transplant relevant to neural development and cell replacement therapies. Using retinal ganglion cells, a type of CNS neuron, as our primary model system in vitro and in rodent models in vivo, we use diverse "omics" and discovery research, combined with hypothesis-driven experiments and novel techniques, to unveil the basis for neuronal development, integration, and regeneration in the visual system.

Orthopedic Surgery

Nidhi Bhutani
Assistant Professor

Bhutani Lab

Our research interests broadly encompass the molecular mechanisms regulating development, regeneration and repair with a focus on the epigenome. We are exploring epigenetic regulation in health and disease especially understanding (a) the dynamics of DNA methylation and demethylation and (b) the 3D chromatin organization. Another focus is stem cell biology and reprogramming approaches especially utilizing embryonic and induced pluripotent stem cells towards musculoskeletal regeneration and for age-associated diseases like Osteoarthritis. 
We are looking for highly creative and motivated postdoctoral fellows with a broad interest in Stem cell biology and Regenerative medicine. The specific research projects are focused on studying epigenetic regulation of skeletal diseases (cartilage and bone) and for understanding stem cell function in skeletal growth and regeneration. Another focus area is tissue engineering and generation of biomimetic 3D tissue models that reflect the endogenous complexity. Applicants must be PhD (cell, molecular or stem cell biology or bioengineering). 

Orthopedic Surgery, (by courtesy) Bioengineering, and Materials Science and Engineering

Yunzhi Yang
Associate Professor 

Yang Lab

My lab's research interests are in the area of biomaterials and medical devices for musculoskeletal regeneration. There are multi position openings for the following projects: 1) multi-tissue healing from muscle to tendon to bone, including rotator cuff injury; 2) bone disease and inflammation such as osteonecrosis of the hip; and 3) large bone trauma and infection, including bioprinting vascularized composite tissues. 

Pathology

Eugene Butcher
Professor 

Butcher Lab

We are interested in fundamental aspects of cell-cell recognition, migration and development with the mammalian immune and vascular systems as  models. We use molecular, genetic and single cell transcriptomic and mass cytometric approaches to study  the development and trafficking of  lymphocytes, NK cells and dendritic cells and their role in immune function in health and diseases. 
 
The vascular endothelium controls immune cell recruitment from the blood,  and thus determines the nature and magnitude of immune and inflammatory responses.     In a major new effort, we are applying single cell approaches (scRNAseq and mass cytometry), and novel computational approaches to probe endothelial cell specialization and responses in models of immune and tumor angiogenesis and inflammation.  
 
Although our focus is on fundamental problems in biology, the work is intrinsically translational and the laboratory is interested in applying its  discoveries to models of infection and immune pathology: examples include genetic studies of GPCR's and assessment of novel therapeutics in models of inflammatory bowel disease, psoriasis, cancer, aging and infection.
 
We are actively recruiting fellows with experience in biocomputation and coding who can take advantage of the datasets we are generating;   or experience in vascular biology, immunology,  imaging and cytometry.

Pathology

Le Cong
Assistant Professor

Cong Lab

In the lab of Dr. Le Cong at Stanford (Pathology and Genetics, Stanford Cancer Institute, Stanford Neuroscience Institute), the overarching goal is to develop cutting-edge gene-editing and genomics technology to understand human diseases, thereby paving the way for precision diagnostics and therapies. We will apply the technology platforms to complex disorders, with one example being to leverage state-of-the-art single-cell CRISPR-Omics approaches to understand cancer immunology. To this end, our interdisciplinary team pioneered a combination of gene-editing and epigenetics tools, high-throughput genomics and sequencing applications in study of immune diseases and neuroscience. Recent work (with selected publications) include:

-Next-generation Gene Editing Technology
(Science 2016, Nature 2015, Cell 2015, Science 2013)

-Single-cell and Systems Biology
(Cell 2017, Cell 2016, Nature Communications 2012)

-Cancer Immunology and Disease Mechanism
(Cell 2016, Cell Reports 2016. Nature Biotechnology 2011)

Our lab has a highly innovative environment and ongoing collaborations with other laboratories at Stanford with expertise in disease-relevant research. This will be a unique opportunity to learn and grow in scientific research, biotechnology development, and translational research with biomedical applications.

Pathology

Michael  Howitt
Assistant Professor 

Our lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.

Pathology

Capucine Van Rechem
Assistant Professor

Van Rechem Lab

Chromatin regulators are highly altered in diseases. Of interest, these proteins are easily targetable by drugs. Furthermore, the plasticity of epigenetic events makes them a powerful target for new therapeutic strategies and reversion of disease phenotype. Histone and DNA modifications influence many processes including transcription, replication, genomic stability and cell division, which are altered in diseases. Therefore, understanding the molecular basis of chromatin modifiers in both normal and pathological cells could help us frame new potential biomarkers and targeted therapies.

My long-term interest lies in understanding the impact chromatin modifiers have on disease development and progression so that more optimal therapeutic opportunities can be achieved. My laboratory explores the direct molecular impact of chromatin-modifying enzymes during cell cycle progression, and characterizes the unappreciated and unconventional roles that these chromatin factors have on cytoplasmic function such as protein synthesis. By gaining molecular understanding into the mechanism of action of chromatin modifiers in normal and pathological cells, we will improve our basic knowledge and provide needed insights into new potential targeted therapies in diseases.

Pathology and Genetics

Andrew Fire
Professor 

Fire Lab

The genetic landscape faced by a living cell is constantly changing.  Developmental transitions, environmental shifts, and pathogenic invasions lend a dynamic character to both the genome and its activity pattern.  We study a variety of natural mechanisms that are utilized by cells adapting to genetic change.  These include mechanisms activated during normal development and systems for detecting and responding to foreign or unwanted genetic activity.  At the root of these studies are questions of how a cell can distinguish "self" vs. "nonself" and "wanted" vs. "unwanted" gene expression.

Pediatrics

Heidi Feldman
Professor

Fledman Lab

My research focuses on the neurobiological basis of language, reading, and cognition in children.  Functional imaging studies demonstrate that language and reading skills require the integrated activity of a network of distributed brain regions.  Diffusion magnetic resonance imaging (dMRI) documents that variations in the properties of long-range white matter pathways connecting these brain regions within the cerebrum and between the cerebrum and cerebellum are associated with variations in language and reading skills.  These white matter pathways may be disturbed in childhood illnesses, such as brain tumors. We have been collecting dMRI scans on children born preterm and full term at different ages, including infancy.  We also have been collecting clinical scans on children with brain tumors in the cerebellum and posterior fossa. We seek students who want to learn techniques for analyzing dMRI and related imaging methods in children and to link the neurobiological findings to clinical outcomes.  Selected studies include: (1) analyzing white matter pathways in preterm infants at near term age in relation to medical and environmental variables; (2) applying spherical deconvolution to scans of children age 6 to 8 years who are learning to read; (3) evaluating longitudinal change in children with mutism after resection of a posterior fossa brain tumor.

Pediatrics

Kathleen Sakamoto
Professor 

Sakamoto Lab

My research focuses on studying normal and aberrant blood cell development. We are interested in understanding the pathogenesis of acute leukemia and bone marrow failure syndromes. We also work with medicinal chemists and computational biologists to develop novel therapies to treat these diseases. 

Psychiatry

Oxana Palesh
Assistant Professor 

Palesh Lab

Project Title: Brief Behavioral Intervention for Insomnia During Chemotherapy. Project Information: Sleep deprivation and disturbance are common problems among breast cancer patients. This study investigates the efficacy of Brief Behavioral Therapy for Insomnia (a form of Cognitive Behavioral Therapy) in treating insomnia in breast cancer patients currently undergoing chemotherapy. Additionally, we are investigating mediators and moderators that affect sleep, such as depression, anxiety, quality of life, and cognitive function. We are also interested in biomarkers and their role in sleep, such as telomeres in blood, cortisol in saliva, and heart rate variability. 
 
Project Title: Prefrontal Cortex Abnormalities Associated with Breast Cancer Chemotherapy (ProBC). Following breast cancer chemotherapy, many women experience cognitive deficits associated with abnormalities in their prefrontal cortex brain structure and function.  This project examines prefrontal cortex structure and function as well as cognitive status in BC patients and controls over multiple years. We utilize neuroimaging (MRI) methods to measure prefrontal cortex volume and functional activation along with neuropsychological measures of executive function, memory, processing speed and attention. We also explore possible predictors of individual outcome utilizing machine learning.

Psychiatry and Behavioral Sciences

Allan Reiss
Professor

Reiss Lab

Dr. Reiss is the Howard C. Robbins Professor and Vice Chair of Psychiatry and Behavioral Sciences, Professor of Radiology and Pediatrics, and a recognized expert in the fields of neuropsychiatry, genetics, neuroimaging, neurodevelopment, and cognitive neuroscience. His research utilizes an interdisciplinary, multi-level scientific approach to elucidate the neurobiological pathways that lead to both typical and atypical behavioral and cognitive outcomes in children and adolescents. He is director of the NIMH funded Research Training for Child Psychiatry and Neurodevelopment program which is currently recruiting for two - three year fellowships. The program is seeking applicants from the fields of psychiatry, psychology, pediatrics, neurology, genetics, neuroscience, developmental biology, computer science and related fields who seek to improve or expand their ability to conduct interdisciplinary- translational research. Physician-scientists accepted into the program can potentially combine the research training program with their clinical training over a 3 to 4 year period.

Psychiatry and Behavioral Sciences

Ranak Trivedi
Assistant Professor

I am most passionate about improving the role of family and friends in the long-term self-management of patients with advanced chronic illnesses. We are spearheading the first ever Center of Excellence to support family caregivers of Veterans and are seeking fellows as collaborators.  I also co-direct the postdoctoral and post-residency fellowships in Health Services Research and Medical Informatics at the VA Palo Alto Health Care System.

Radiation Oncology

Richard Frock
Assistant Professor

Frock Lab

The Frock laboratory is interested in elucidating mechanisms of DNA double-stranded break (DSB) repair and chromosome translocations.  We employ a high-throughput sequencing technology that identifies and maps cellular DSBs.  We are interested in further developing this technology to more fully quantify the DSB repair fates from targeted DSBs.  Our research disciplines are broad and cover aspects of molecular and cancer biology, bioinformatics. immunology, genome editing, and radiation biology.

Radiation Oncology

Edward Graves
Associate Professor

Graves Lab

The Graves laboratory in the Department of Radiation Oncology at Stanford University is focused on development and application of molecular imaging techniques to study the radiobiology of cancer and normal tissue and to improve the efficacy radiotherapy of cancer.  These efforts balance engineering of novel methods to image biologically and clinically important aspects of the tumor microenvironment with application of these techniques to understand how cells and tissues respond to radiation.  This work has included basic research on the effects of radiation on tumor cell migration and the ability of radiation to stimulate systemic cytokine and immune responses, evaluations of the ability of imaging methods to detect hypoxia and the role of oxygenation in preclinical studies, and investigation of the prognostic performance of clinical imaging modalities.  In addition, we have engineered novel methods for small animal radiotherapy as well as multimodal molecular image acquisition and analysis.  We are a multi-disciplinary group with expertise in engineering, biology, chemistry, medicine, and computer science.

Radiology

Shreyas Vasanawala
Professor

We are seeking a talented individual for a research associate position in our multidisciplinary team. Our advanced pediatric MRI research program spans across novel developments in hardware, pulse sequences, machine learning algorithms, image reconstruction methods, and image analysis techniques, all with an integrated clinical translational component. Efforts bridge across multiple departments on the Stanford University campus and UC Berkeley, as well as with Silicon Valley companies. The position offers the opportunity to work with multiple faculty, post-doctoral scholars, graduate students, and undergraduates. Responsibilities include developing novel techniques, contributing to grant proposals, writing and submitting manuscripts, and developing intellectual property.

Radiology

Michael Zeineh
Assistant Professor 

Zeineh Lab

My lab focuses on translating advanced MRI into clinical practice. In Alzheimer's disease, we are investigating the nature of iron deposition to understand how iron interacts with inflammation, amyloid, and tau in the progression of AD. We bring to this disease the full arsenal of imaging: ultra-high resolution MRI of human AD specimens coupled with novel histological methods including x-ray microscopy and electron microscopy. We bring this armamentarium full circle to living human imaging with 7.0T MR and multi-tracer PET-MR. In mild traumatic brain injury, we are studying the imaging signatures of brain insult that occur in high-contact sports using advanced MRI combined with mouthguard accelerometer measurements of impacts. In chronic fatigue syndrome, we are identifying microstructural changes that accompany fatigue and correlate with systemic circulating cytokines that together may form a biomarker for this disorder.

Stanford Cardiovascular Institute

Joseph Wu
Professor & Director

Wu Lab

Our lab works on biological mechanisms of patient-specific and disease-specific induced pluripotent stem cells (iPSCs). The main goals are to (i) understand basic cardiovascular disease mechanisms, (ii) accelerate drug discovery and screening, (iii) develop “clinical trial in a dish” concept, and (iv) implement precision cardiovascular medicine for prevention and treatment of patients. Our lab uses a combination of genomics, stem cells, cellular & molecular biology, physiological testing, and molecular imaging technologies to better understand molecular and pathophysiological processes.

Surgery

Electron Kebebew
Professor 

Endocrine Oncology Research Lab

The Endocrine Oncology Research Laboratory is engaged in cutting-edge endocrine and neuroendocrine clinical, translational and basic research. Our research is focused on:
- Identifying the molecular basis of endocrine cancers that could impact patient care.
- Creating new and improved methods, strategies, technologies, and algorithms for the diagnosis of endocrine neoplasms.
- Defining genetic testing criteria, and optimal screening and surveillance strategies for inherited endocrine and neuroendocrine syndromes.
- Discovering new molecular, genetic, proteomic, and metabolomic markers for developing better diagnosis and novel targets for treatment of metastatic and advance endocrine and neuroendocrine cancers or biomarkers which could predict prognosis/response to surgical therapy.
- Advanced imaging and genetics that will allow for precision endocrine surgery.

Surgery – Abdominal Transplantation

Olivia Martinez
Professor (Research)

Martinez Lab

My laboratory has a long-standing interest in host-pathogen interactions.  In particular, we are analyzing the immune response to Epstein Barr virus (EBV) and cytomegalovirus (CMV).  We are currently using single cell approaches to define the T cell receptor repertoire and functional properties of T cells associated with protection against the virus.  We are recruiting post-doctoral fellows that can contribute to single cell transcriptomics studies and computational analysis of anti-viral T cell receptor repertoires.

 

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