The labs of Keith Van Haren MD (Depts of Neurology & Pediatrics) and Zihuai He PhD (Depts of Neurology & Medicine) at Stanford University have a postdoctoral position available for candidates with prior training in bioinformatics, cell metabolism, epigenetics, immunology, or systems biology.
The Van Haren lab elucidates factors that confer metabolic resilience and vulnerability in the developing brain and immune system. Our experimental work is typically centered around human tissue from clinical trials or post-mortem biobanking with supporting work in model systems (e.g. murine, C. Elegans). We utilize both structured trials for pediatric patients as well as model organisms, employing multi-omic analyses in to address both clinical and fundamental questions about human development. A primary focus of our work is to resolve the pathways linking perturbations in lipid metabolism with neuroinflammatory pathologies. Adrenoleukodystrophy and multiple sclerosis serve as our principle disease models.
The lab of Dr Zihuai He specializes in the development of new statistical methodologies that use integrated, multi-omic analysis to identify and interpretat complex biological pathways involved in human neurological disorders. Dr He's methodologic interests includes high-dimensional data analysis, correlated (longitudinal, familial) data analysis and machine learning algorithms.
The successful candidate will use multi-omic immune cell signatures from our lab’s clinical trial of vitamin D in children along with paired mouse experiments to investigate vitamin D-enabled pathways relevant to developmental resilience in brain and blood. The candidate will also be encouraged to develop their own lines of inquiry.
Dr Van Haren and Dr He are dedicated mentors interested in helping young scientists build their careers in academia, industry, and beyond. The position is well-suited to scientists who want to understand the human context of their science and/or learn how to better apply their skills directly toward the alleviation of human disease.
- We are interested in candidates who work collaboratively, think creatively, and have a good publication record.
- An ideal candidate should have should have fewer than three (3) years postdoctoral experience as well as solid training in at least one of the following fields: bioinformatics, cell metabolism, epigenetics, immunology, or systems biology.
1. Cover letter that briefly describes your career goals, research interests, and past accomplishments
3. Contact information for 3 professional references
4. Your most recent or relevant publications