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Open Postdoctoral position, faculty mentor Vinit Mahajan

Important Info

Faculty Sponsor (Last, First Name): 
Mahajan, Vinit
Stanford Departments and Centers: 
Ophthalmology
Postdoc Appointment Term: 
1 year, with possibility of extension
Appointment Start Date: 
ASAP
How to Submit Application Materials: 

To apply, please complete this application form and include all pertinent documents: https://app.smartsheet.com/b/form/c7da3b8be87f4e228a7b0b74dfac1674 

Prof. Vinit Mahajan’s group in Department of Ophthalmology, Stanford School of Medicine is seeking applications for a postdoctoral fellow position from ambitious, enthusiastic, and recent Ph.D. holders or graduate students who are expecting to finish his/her graduate degree in structural biology, biophysics, biochemistry, bioengineering, molecular cell biology, or pharmaceutics. The successful candidate will be a structural biologist with strong interests in biomedical, translational, and pharmaceutical sciences, who can carry out one or few structural biology projects for eye disease proteins. Dr. Mahajan is a physician/surgeon, and a scientist, who is the vice chair for research and the director of Molecular Surgery Program of the Stanford’s Byers Eye Institute. He runs a large interdisciplinary group of scientists and clinicians, who are actively seeking for therapeutics and cure for eye patients (https://mahajanlab.stanford.edu/). Mahajan group is in a close collaboration with Prof. Soichi Wakatsuki, Structural Biology Department, Stanford School of Medicine and SLAC National Accelerator Laboratory (http://med.stanford.edu/wakatsukilab.html). Dr. Wakatsuki leads Biosciences Division of Stanford Synchrotron Radiation Lightsource (SSRL) Directorate at SLAC. Dr. Wakatsuki’s interests cover protein-protein interactions (Comerci et al. Nat. Comm. 2019; Herrmann et al. PNAS 2019), enzyme dynamics (Stoffel et al. PNAS 2019), and structure-based drug design (Hwang et. al., Nat. Comm. 2018).

Both Drs. Mahajan and Wakatsuki are members of Stanford BioX and ChEM-H, interdisciplinary institutes encompassing three Stanford Schools: Medicine, Chemistry, and Engineering. This provides a truly interdisciplinary research environment at the crossroad of medical science, structural biology and state-of-the art bioimaging technologies. The two groups collaborate closely on structural biology research on eye disease proteins. See one of our recent publications on the structure-function investigation of a cysteine protease: Calpain-5 (Velez et al. Cell Reports 2020). Other ophthalmologic structural biology work includes: 1) targeted structure-functionomics for eye diseases; and 2) structure-based drug design for retinal degeneration.
SLAC provides state-of-the-art multi-modal structural biology technologies covering wide range of spatiotemporal resolutions. SLAC hosts large scale infrastructures: SSRL Structural Molecular Biology (SMB), and Linac Coherent Light Source (LC/LS) providing synchrotron and X-ray beams for crystallography, scattering and spectroscopy, and Stanford-SLAC CryoEM Center (S2C2) providing access to the cryoelectron microscopy (CryoEM) instruments for both single particle structural analysis and tomography (CryoET).

Required Qualifications: 
  • Ph.D. or equivalent degree in the relevant fields within the last 3 years.
  • English proficiency is mandatory.
  • Familiarities with one or more of structural biology techniques, including X-ray crystallography, small angle X-ray scattering, cryoEM/ET, biocomputation, and hybrid methods.
  • Strong background and experiences in sample preparation and characterization.
  • The applicant must be a good team player.
  • Experiences in scientific writing and grant application to US funding agencies are plus.
Required Application Materials: 
  • Updated CV
  • Cover Letter
  • References with contact information

 

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.