Please email Dr. DiRenzo at email@example.com with the required application materials.
The DiRenzo laboratory in the Division of Laryngology within the Department of Otolaryngology – Head & Neck Surgery is seeking a highly-motivated postdoctoral scholar to join our team. Our group studies the cellular and molecular events leading to the development of voice and upper airway disorders. An overarching goal of our research is to translate discoveries from the laboratory into the clinic to improve patient management.
The postdoctoral scholar will work on a new NIH-funded R01 project aimed to demonstrate that laryngeal basal cells are essential to normal epithelial homeostasis and test whether this cell population is implicated in the pathogenesis of cigarette smoke-mediated injury and disease. Our prior studies identified the earliest abnormalities associated with cigarette smoke is laryngeal epithelial remodeling, with the first histologic change being basal cell hyperplasia. Here, we will extend this programmatic line of inquiry using in vivo mouse and in vitro cell culture injury models of cigarette smoke exposure established in our laboratory. Specifically, the successful candidate will lead a project that seeks to determine whether increasing doses of cigarette smoke administered in vitro impairs the ability of cultured laryngeal basal cells to form a functionally differentiated epithelium.
We are looking for a motivated, creative, and qualified scientist with excellent written and verbal communication skills. Women and under-represented minorities in academia are strongly encouraged to apply.
• PhD and/or MD degree in life sciences, medicine, or related fields conferred prior to start date
• Prior experience working in a research lab
• Prior experience in mammalian/human airway cell culture in monolayer and air-liquid interface
Preferred skills include any of the following:
• Prior experience in immunostaining, confocal microscopy, animal models, and/or next generation sequencing
• Prior experience working in airway biology and / or toxicology
• Prior experience with in vivo and / or in vitro inhalation models
• A brief cover letter highlighting prior experience and reasons for interest in the position
• Names and contact information for 2-3 references
• Copies of key prior paper(s) led by the applicant