We are a highly interdisciplinary research team, joined in our desire to derive a more mechanistic understanding of prokaryotic life.
To elucidate how bacterial cells accumulate biomass and grow, we study the model organism Escherichia coli. Our approaches tightly combine quantitative experimentation with mathematical modeling to consider the coordination of major physiological processes across scales; from metabolism and protein synthesis, via cell-size control, to swimming.
We further focus on gut bacteria and their interactions with each other and the human host. Our analyses include considerations of intestinal physiology and diet habits on the host side, as well as metabolism, growth-physiology, ecology, and evolution on the bacterial side.
