Samuele Marro

Publication Details

• Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression.

  Marro S, Barisani D, Chiabrando D, Fagoonee S, Muckenthaler MU, Stolte J, Meneveri R, Haile D, Silengo L, Altruda F, Tolosano E. Gastroenterology. 2007; 133 (4): 1261-1271

  Haptoglobin is an acute phase protein responsible for the recovery of free hemoglobin from plasma. Haptoglobin-null mice were previously shown to have an altered heme-iron distribution, thus reproducing what occurs in humans in cases of congenital or acquired anhaptoglobinemia. Here, we report the analysis of iron homeostasis in haptoglobin-null mice.

  PubMedID: 17919498