Stanford University

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  • Jonathan Nizar

    Jonathan Nizar

    Clinical Instructor, Medicine - Nephrology

    Current Research and Scholarly Interests Diabetes and hypertension are among the most common diseases treated in the US. The combination of these disease greatly increased the risk of heart attack, stroke, and early death. While over 90% of patients with diabetes have high blood pressure, its cause is unknown. Working in the laboratory of Vivek Bhalla, I am interested in understanding the mechanisms that diabetes contributes to high blood pressure. We current are focused on the regulatory role of insulin on sodium reabsorption in the kidney, which is a master regulator of blood pressure. Using a mouse model of diabetes and transgenic technologies, we utliize classical metabolic experiments, expression, electrophysiological, and primary cell culture techniques to understand the role of insulin in regulating sodium transport in the kidney, blood volume in the body, and increased blood pressure in diabetes.

  • Xiaoyi Zheng

    Xiaoyi Zheng

    Postdoctoral Research Fellow, Nephrology

    Current Research and Scholarly Interests I hope you have a happy day with your research!

    Nephrology (postdoc 2013-current)

    Diabetes causes kidney disease in 40% of the patients, and people don`t know which gene(s) causes the differential susceptibility to kidney disease. By using modern biotechnology such as microarray, I aim to identify the genes that cause diabetic kidney disease. These genes may become biomarkers for early diagnosis or new therapeutic targets for treatments. My expertise includes primary cell isolation and flow cytometry, IHC/IF (paraffin and frozen), WB/qPCR, establishing ELISA methods, chromatography, cell culture, animals/i.v. injection/hydrodynamic injection. I have a 3-year postdoctoral fellowship from Larry L. Hillblom Foundation.

    Cancer (Ph.D 2009-2013)

    Late diagnosis of cancer often causes death due to metastasis. By establishing ELISA method to detect a new cancer marker, I aim to detect cancer early so that the doctors can eliminate death. This new cancer marker and ELISA method are patented or under patent application. I further studied the biological function of this cancer marker to discover a new therapeutic target.

    Communication facilitator (2014-current)

    A scientist needs communications to promote their research. I learned scientific communication in Stanford Leadership in Communication (workshop), and later become a facilitator in the workshop to coach beginners.

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